Furthermore, similar lesions were not observed in the rat or mouse following subchronic or chronic dietary exposure, and there was no other evidence in any species tested to indicate a neurotoxicity potential. This table of contents is a navigational tool, processed from the In making its tolerance decisions, EPA seeks to harmonize U.S. tolerances with international standards whenever possible, consistent with U.S. food safety standards and agricultural practices. The objective of this work was to evaluate the effect of trinexapac-ethyl and nitrogen doses on the agronomic performance and grain yield of three wheat cultivars. Based on current evidence, plant growth regulators in Oklahoma are best kept on acres with high (> 80 bu/ac) yield potential that may have greater propensity for lodging due to variety or fertility. document.write(" Hide\u00A0index<\/span><\/a>\u00A0|")
documents in the last year. Design Philosophy From Female Golf Course Architects. EPA has evaluated the available toxicity data and considered its validity, completeness, and reliability as well as the relationship of the results of the studies to human risk. Chastain, M.P. Palisade did not affect lodging at Perkins in 2013. Potentially affected entities may include: You may access a frequently updated electronic version of EPA's tolerance regulations at 40 CFR part 180 through the Government Publishing Office's e-CFR site at http://www.ecfr.gov/cgi-bin/text-idx?&c=ecfr&tpl=/ecfrbrowse/Title40/40tab_02.tpl. 2. developer tools pages. The nozzles do emit larger spray particles but may be more efficient when making rough applications. documents in the last year, 822 Box 18300, Greensboro, NC 27419. Substance Name: Trinexapac-ethyl [ISO] RN: 95266-40-3 UNII: Q89W563T9J InChIKey: RVKCCVTVZORVGD-QXMHVHEDSA-N. [FR Doc. Short-, intermediate-, and chronic-term risks are evaluated by comparing the estimated aggregate food, water, and residential exposure to the appropriate PODs to ensure that an adequate MOE exists. Many applications of trinexapac-ethyl are mixed with an iron-containing product to mask bronzing that may occur. How doesTrinexapac-ethyl work? document.write(" Prin<\/span>t<\/a> ![\"Print\"](\"print-icon.png\" "\\"Print"){kind=icon}
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EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. Combustible. 101 Madison Avenue Trinexapac-ethyl is a synthetic plant growth regulator that is derived from cyclohexanecarboxylate. Prenatal and postnatal sensitivity. Roanoke, VA 24016. The toxicology database for trinexapac-ethyl is largely complete, with the exception of a subchronic neurotoxicity study, which is a new data requirement under 40 CFR part 158 for registration of a pesticide (food and non-food uses OPPTS 870.6200b). 1501 et seq.). Additionally, T-NEX is the perfect pre-stress conditioning choice for the coming season. 21 U.S.C. Document Drafting Handbook Wheat plant heightas affected by plant growth regulators in 2013, Wheat plant height as affected by plant growth regulator in 2014. Therefore, tolerances are established for residues of trinexapac-ethyl, including its metabolites and degradates, as set forth in the regulatory text. 2020-23040 Filed 11-3-20; 8:45 am], updated on 4:15 PM on Tuesday, February 28, 2023, updated on 8:45 AM on Tuesday, February 28, 2023, 104 documents ), do not apply. Counts are subject to sampling, reprocessing and revision (up or down) throughout the day. Carefully collect remainder. Find your Trinexapac-ethyl order with 70000+ buyers on ECHEMI. The product may cause mild eye irritation. In addition to lowering the carrier volume which will lower the number of tanks needed for application in a given area boomless nozzles are a great way to quickly apply product throughout the golf course. Objections and requests for hearings must be received on or before January 4, 2021, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. %%EOF
has no substantive legal effect. Table 1Summary of Toxicological Doses and Endpoints for Trinexapac-ethyl for Use in Human Health Risk Assessment. Only official editions of the headings within the legal text of Federal Register documents. * * *. Trade Capacity. Developmental rabbit study. Incidental oral (short and intermediate-term), No appropriate endpoint for the incidental oral scenario for children, Dermal & Inhalation (short- and intermediate-term-adults only), Dermal (or oral) study NOAEL = 60 mg/kg/day (dermal absorption rate = 77.5%. Getting the most out of these applications is more important than ever as every minute of maintenance is especially valuable during these challenging times. Use the PDF linked in the document sidebar for the official electronic format. Thus, the Agency has determined that Executive Order 13132, entitled Federalism (64 FR 43255, August 10, 1999) and Executive Order 13175, entitled Consultation and Coordination with Indian Tribal Governments (65 FR 67249, November 9, 2000) do not apply to this final rule. Federal Register provide legal notice to the public and judicial notice Therefore, 40 CFR chapter I is amended as follows: 1. endstream
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The telephone number for the Public Reading Room is (202) 566-1744, and the telephone number for the OPP Docket is (703) 305-5805. Trinexapac-ethyl is used to control the growth on various grass species and crops. It is used to control the growth on various grass species and crops. Monks, T.G. Since tolerances and exemptions that are established on the basis of a petition under FFDCA section 408(d), such as the tolerance in this final rule, do not require the issuance of a proposed rule, the requirements of the Regulatory Flexibility Act (RFA) (5 U.S.C. Refer for medical attention . 272 note). S-4400, One Potomac Yard (South Bldg. Trinexapac-ethyl is classified as "Not likely to be carcinogenic to humans." The combined chronic toxicity/carcinogenicity study in the rat did not demonstrate an increase in any tumor type that would be relevant to humans. It is interesting to note that the Palisade treatment increased grain yield at Perkins even though the plots lodged at comparable levels as the non treated check. The mean recoveries of trinexapac-ethyl and trinexapac in four matrices at three spiking levels ranged from 72.0% to 108.2%, and the relative standard deviation (RSD) ranged from 2.1% to 11.0%. Human Health Risk Assessment for the Petition to Amend the Pre-Harvest Intervals on Sugarcane. dated July 13, 2020 in the docket ID number EPA-HQ-OPP-2020-0046. Similar lesions were not observed in the rat or mouse following acute, subchronic or chronic dietary exposure, and there was no other evidence in any other species tested to indicate a neurotoxicity potential. 3. by the Patent and Trademark Office To ensure proper receipt by EPA, you must identify docket ID number EPA-HQ-OPP-2010-0524 in the subject line on the first page of your submission. documents in the last year, 522 The numbers in the figure do not account for harvest losses, which can exceed losses associated with lower photosynthetic capacity shown in the figure. The finer the spray particle size, the more uptake and suppression you're likely to get. P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. Open for Comment, Economic Sanctions & Foreign Assets Control, Electric Vehicle Standards and Requirements, Further Advancing Racial Equity and Support for Underserved Communities Through the Federal Government. documents in the last year, 287 SEARCH. Prevent fire caused by electrostatic discharge steam. That is, a plant growth regulator will not make a lodging prone variety stand like one with excellent straw strength, rather they will make it less prone to lodging relative to the same variety non treated. Sign in to access your AXS Fan Account to manage your tickets. NO open flames. Recommendations may change as further research is conducted and new information is obtained. These tools are designed to help you understand the official document Other names: Trinexapac-ethyl, trimethylsilyl ether Permanent link for this species. Be sure to consider the method of trinexapac-ethyl application when trying to maximize effectiveness. documents in the last year, 24 This regulation is effective March 2, 2012. Pesticide manufacturing (NAICS code 32532). Use the PDF linked in the document sidebar for the official electronic format. . The Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. the Federal Register. Marietta Echeverria, Registration Division (7505P), Office of Pesticide Programs, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001; main telephone number: (703) 305-7090; email address: RDFRNotices@epa.gov. documents in the last year, 861 EPA has sufficient data to assess the hazards of and to make a determination on aggregate exposure for Trinexapac-ethyl including exposure resulting from the tolerances established by this action. Full disclosure: Syngenta donated the product for this trial, but the only funding for the research was provided by the Oklahoma Agricultural Experiment Station and the Oklahoma Cooperative Extension Service. Trinexapac-ethyl (Ref: CGA 163935) (Also known as: trinexapac; cimectacarb-ethyl; cimectacarb) The following alerts are based on the data in the tables below. documents in the last year, 662 We rated plots for lodging at harvest using a 1 10 scale with 0 equaling no lodging and 10 equaling complete lodging. %PDF-1.6
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Consistent with FFDCA section 408(b)(2)(D), and the factors specified in FFDCA section 408(b)(2)(D), EPA has reviewed the available scientific data and other relevant information in support of this action. Register documents. establishing the XML-based Federal Register as an ACFR-sanctioned documents in the last year, 822 III. 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylic acid, Growth Retardant Effects Caused By Interfering With Gibberellin Biosynthesis, Plant Growth Regulators (Unclassified Plant Growth Regulators) [1]. Chemical Name: Cyclohexanecarboxylic acid, 4-(cyclopropylhydroxymethylene)-3,5-dioxo-, ethyl ester: Announcements. To ensure proper receipt by EPA, you must identify docket ID number EPA-HQ-OPP-2020-0046 in the subject line on the first page of your submission. Each document posted on the site includes a link to the 272 note). Monoisotopic mass 252.099777 Da. Upon review of the available information, EPA concludes that these tolerances would be safe. 02/28/2023, 828 Apply using a medium quality spray using a spray pressure of 2-3 bar. You must file your objection or request a hearing on this regulation in accordance with the instructions provided in 40 CFR part 178. Trinexapac-ethyl. More information and documentation can be found in our 95266-40-3. Classification Codes. Register, and does not replace the official print version or the official You may be potentially affected by this action if you are an agricultural producer, food manufacturer, or pesticide manufacturer. The thicker the wheat crop and/or the taller the wheat crop, the more force that winds exert on the root anchorage system and the greater the likelihood of lodging. Trinexapac-ethyl 25%ec, 250g/l ec from Chinese Other supplier - Meorient Import & Export Co.LTD on tradechina.com. That notice referenced a summary of the petitions prepared by Syngenta Crop Protection, Inc., the registrant, which is available in the docket, http://www.regulations.gov. The Codex has established an MRL for trinexapac-ethyl in or on sugarcane at 0.5 ppm. rendition of the daily Federal Register on FederalRegister.gov does not documents in the last year, 36 Latest Registration Process: Registration Review . All Rights Reserved. Compliance with the tolerance levels is to be determined by measuring both trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and the associated metabolite trinexpac, 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent of trinexapac-ethyl. that agencies use to create their documents. That is, a plant growth regulator will not make a lodging prone variety stand like one with excellent straw strength, rather they will make it less prone to lodging relative to the same variety non treated. The method may be requested from: Chief, Analytical Chemistry Branch, Environmental Science Center, 701 Mapes Rd., Ft. Meade, MD 20755-5350; telephone number: (410) 305-2905; email address: residuemethods@epa.gov. Acute dietary risks are below the Agency's level of concern: 2.5% of the acute population adjusted dose (aPAD) for females 13 to 49 years old, the population group of concern. documents in the last year, 940 The goal to is to apply trinexapac-ethyl only to the leaf as this is the only route of uptake into the plant. on Emergency exemptions may be requested by a state or federal agency. 1. Comments were received on the notice of filing. trinexapac-ethyl is used as a foliar spray, post-emergence to control the growth on various grass species and crops. Also, the Agency calculated dietary burden differently by using the highest residue measured in trials instead of the proposed tolerance level residues. Additionally, T-NEX is the perfect pre-stress conditioning choice for the coming season. Quantitative acute dietary exposure and risk assessments are performed for a food-use pesticide, if a toxicological study has indicated the possibility of an effect of concern Start Printed Page 12743occurring as a result of a 1-day or single exposure. to the courts under 44 U.S.C. Palisade did not affect lodging at Perkins. There was no lodging for any site or treatment in 2014. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866, entitled Regulatory Planning and Review (58 FR 51735, October 4, 1993). Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. developer tools pages. documents in the last year, 37 if (window != top)
This action modifies existing tolerances under FFDCA section 408(d) in response to a petition submitted to the Agency. 1035 0 obj
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Prevent further spillage or leakage if it is safe to do so. Wheat lodging is not generally a widespread problem in Oklahoma, but it does occur. (a) General. 2. documents in the last year, 87 I the absence of weakened stems due to freeze or disease, most lodging in wheat is caused by failure of the root anchorage system (root lodging). documents in the last year, 474 Our senior, well-informer and skilled sales team is able to offer customers professional and efficient service. This site displays a prototype of a Web 2.0 version of the daily Information about this document as published in the Federal Register. Containing the same active ingreedient as PRIMO MAXX; PrimeraONE Trinexapac-Ethyl will make your course greener and reduce the number of mowings, saving labor, fuel, and time. documents in the last year, 1479 There is the potential for incidental oral exposure; however, since there is no toxicological endpoint of concern for that route, a quantitative assessment was not conducted. Although EPA recognizes that some individuals would oppose any use of pesticides on food, section 408 of the FFDCA authorizes EPA to set tolerances for residues of pesticide chemicals in or on food when it determines that the tolerance meets the safety standard imposed by that statute. 2015. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866, entitled Regulatory Planning and Review (58 FR 51735, October 4, 1993). Lodging at head emergence can cause as little as 30 or as much as 80% yield reduction. All risk estimates are below EPA's level of concern. Experiments were conducted in New Jersey to investigate efficacy and absorption of bispyribac-sodium applied with trinexapac-ethyl for annual bluegrass control and turfgrass tolerance. Until the ACFR grants it official status, the XML Quality CAS 95266-40-3 Trinexapac-ethyl - find quality Agrochemical Pesticide, Organic Acid & Agrochemical Pesticide from Hebei Luantong trade.co of China Suppliers - 168640825. . See what the USGA is doing to ensure a strong future for the game. The President of the United States manages the operations of the Executive branch of Government through Executive orders. However, to the best of our knowledge, TE has not been used to study the requirement of GAs in onset of germination. An anonymous citizen objected to the presence of any pesticide residues on food. Freeze injury or disease can cause lodging due to stem failure, which is characterized by plant stems breaking near the base. The reasons for these changes are explained in Unit IV.D. X. . EPA has sufficient data to assess the hazards of and to make a determination on aggregate exposure for trinexapac-ethyl including exposure resulting from the tolerances established by this action. Similarly, EPA does not believe that the non-dietary residential exposures are underestimated because they are based on the conservative assumptions of EPA's Draft Standard Operating Procedures (SOPs) for Residential Exposure Assessments (December 1997), and updates contained in the Science Advisory Council Policy 12 (February 2001) as well as the uses specified in the proposed labels. EPA is revising the tolerance expression to include the free and conjugated forms of the parent (trinexapac-ethyl) and acid. Please store the product under the recommended conditions in the Certificate of Analysis. documents in the last year, 940 Based on the Pesticide Root Zone Model/Exposure Analysis Modeling System (PRZM/EXAMS) and Screening Concentration in Ground Water (SCI-GROW) models, the estimated drinking water concentrations (EDWCs) of trinexapac-ethyl for acute exposures are estimated to be 12.61 parts per billion (ppb) for surface water and 0.009 ppb for ground water. Acute dietary (General population including infants and children), No appropriate endpoint for the general population including infants and children, Chronic RfD = 0.32 mg/kg/day cPAD = 0.32 mg/kg/day. Trinexapac-ethyl (TE), a GA synthesis inhibitor, is frequently used as a plant growth regulator in crop production. Using the exposure assumptions described in this unit, EPA has concluded the combined food, water, and adult post-application dermal exposures result in aggregate MOEs of 761 for liquid products and 601 for granular products. Revising the existing entries in the table for Sugarcane, cane and Sugarcane, molasses. Tech Grade: 96% TC: Formulation: 25% EC . The petition requested that 40 CFR part 180.662 be amended by establishing tolerances for residues of the herbicide trinexapac-ethyl, (4-(cyclopropyl-a-hydroxy-methylene)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester), and its primary metabolite CGA-179500 in or on sugarcane, cane at 1.5 parts per million (ppm) and sugarcane, molasses at 5.0 ppm.